Organized by Nate and Eric Gamazon from Vanderbilt University Medical Center, this compendium in Circulation Research highlights single cell research in cardiovascular system. While each contribution, including that from Bob, Nate, and collaborator Kaushik Amancherla (VUMC) https://doi.org/10.1161/CIRCRESAHA.125.326002 , shares a retrospective review of past work, each is also forward looking: Where does single cell research go from here? Read more in https://doi.org/10.1161/

Anna Zamperetti, undergraduate student at Lemoyne University, and long time team member of the Tucker lab (summer fellowship, in semester research, paid summer employment), will be attending the University of Buffalo next fall to begin her PharmD program. Biggest congrats to Anna, and thanks for all the hard work and dedication in the lab over the years. Few publications with your name on them yet to come!

Continuing our long-standing productive collaboration with Emily Tsai's group at Columbia, this publication identifying a unique mechanism for female specific adaptation to right ventricular remodeling. While cardiology has traditionally spent the vast majority of focus and effort on the left ventricle, which controls systemic circulation, right ventricular function is a critical predictor of heart failure, especially that with preserved ejection fraction. Here, Emily's group

Michelle Lance, who first joined the Tucker lab as a computational biologist back in 2020 (feels like forever ago), has accepted a position in the Neuroscience Department here at Upstate, where she will lead bioinformatics efforts across many groups and projects. Since joining the lab fresh out of her PhD at Cornell University, Michelle has been an absolutely critical member of the group, leading the majority of our single cell analyses while also being an excellent team play

Identifying biomarkers for atrial fibrillation is a critical gap to address in the face of underdiagnosis, especially in light of the severe impacts of AF on morbidity and its increasing population prevalence. Working with collaborators from across the pond, the Fabritz group identified BMP10 as a crucial biomarker for AF and established its impact on stem cell derived cardiomyocyte models, notably upregulating TGFB pathway members and genes linked to AF and heart failure. Bo

Leveraging human tissue resources to uncover critical biology is at the heart (no pun intended) of our research mission. Partnering with...

How can we prioritize biomarkers and therapeutic targets in pressure overload induced cardiac dysfunction? In this collaborative effort,...

Results of a long-term collaborative effort from the Wrann Lab at Mass General Brigham and the Tucker Lab at SUNY Upstate, highlighting...

Our first intramural collaboration at Upstate. Led by David Auerbach's group in the Department of Pharmacology, a new rabbit model...

One of our first single cell studies of the microfluidic era finally out in print. The rat presented several unique challenges for our...

Anna Zamperetti, undergraduate student at Lemoyne University, joins the lab as a visiting student researcher. Previously a summer fellow...

New study highlighting transcriptional differences in the left atrium of individuals with a history of atrial fibrillation. One of the...

New study examining concerning off target activation of widely used Myh6 Cre lines which are traditionally used to study cardiac specific...

New study on prioritizing targets in the circulating proteome for putative cardiac origin in heart failure. Co-led by Dr. Tucker and...

Rezwana Karim comes to us following her successful PhD at Cornell University where she focused on how cells adapt to nutrient deprivation...

After four productive years at the Masonic Medical Research Institute, our group moved to the Department of Pharmacology at SUNY Upstate...